Description: Drotaverine and mefenamic acid provide relief from abdominal pain, cramps, and spasms associated with conditions such as gastroesophageal reflux disease (GERD) and constipation. Mefenamic Acid is a non – narcotic anti-spasmodic that acts directly on the smooth muscles of the intestine to provide pain relief. Both drotaverine and mefenamic acid work to decrease muscle contractions in the intestine to relieve symptoms of GERD and constipation.